LAB MEMBERS

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Dr. Kyle K. Biggar, Ph.D.

Lab Head

Professional Experience:

2016 - present - Assistant Professor, Carleton University

2013-2016 - NSERC/BantingPostdoctoral Fellow, Western University (Dr. Shawn Li)

2008-2013 - Ph.D. student, Carleton University (Dr. Kenneth Storey) 

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Dr. Valentina Lukinovic, Ph.D.

Postdoctoral Researcher

Dr. Lukinovic's research is focused on the design and development of peptide inhibitors for methyltransferase inhibitors for use as both cancer therapeutics and tools to study methyllysine biology. Currently, she is working to develop peptide inhibitors for METTL enzymes.

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Matthew Hoekstra, B.Sc.

Ph.D. Candidate

Matt's research is focused on the development of innovative ways to explore and annotate KDM enzyme-substrate networks. This involves the development of novel detection assays, as well as new systematic substrate screens to determine preferences. Matt's Ph.D. thesis is focused on the KDM5 family of demethylase enzymes.

 

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Francois Charih, M.A.Sc., B.Sc., B.A.Sc.

Ph.D. Candidate (NSERC PGS-D)

Francois's research interests are focused on the implementation and development of computational resources to explore the methyllysine proteome. This includes the combination of machine learning with large proteomic databases to help guide wet-lab validation experiments. He is a co-supervised student with Dr. James Green. 

 

Anand Chopra, B.Sc.

Ph.D. Candidate (NSERC CGS-M & PGS-D)

Anand's research is focused on uncovering the hypoxia-responsive functions of the demethylase, KDM3A. His thesis systematically explores KDM3A substrate recognition preferences and uses this knowledge to identify potential roles in hypoxia adaptation. He is a co-supervised student with Dr. Bill Willmore. 

 

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Nashira Grigg, B.Sc.

M.Sc. Candidate 

Nashira is an experienced Data Scientist with a demonstrated history of working in the public safety industry. Skilled in Bioinformatics, Biosafety, Statistical Data Analysis, Laboratory Methods, and Computer Science. 

 

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Ali Shukri, B.Sc.

M.Sc. Candidate 

Ali is a Protein Biochemist with an interest in peptides. He is working to design new antimicrobial peptides through the use of combinatorial peptide synthesis and systematically mutated peptide arrays. He is currently working on developing beta-lactamase inhibitors in collaboration with Dr. Alex Wong (co-supervisor).

UNDERGRADUATE LAB MEMBERS

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Emine Topcu

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Abhi Kurusetty

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Lucas DiRienzo

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Justin Connolly